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Past and Recently Developed Boron Delivery Agents After the first efforts, during the 1940s and 1950s, using the simplest boron salts including disodium tetraborate and sodium pentaborate, it became clear that a selective and high boron accumulation in tumor cells is crucial for an application in BNCT (Farr et al., 1958) and sodium mercaptoundecahydro- closo -dodecaborate (BSH) (Soloway et al., 1967) were found to accumulate in the desired tissues in sufficient amount (Figure 9A)
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