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FUNDING INFORMATION This work was supported by the “Xingliao Talents Program” of Liaoning Province (XLYC2008010), the National Natural Science Foundation of China (Nos 82272940 and 81972515), the science and technology support program of Liaoning Province (2022JH2/20200075), and the 345 Talent Project and Shengjing Scholar Program of Shengjing Hospital of China Medical University
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