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First-in-human phase 1 study of the arginase inhibitor INCB001158 alone or combined with pembrolizumab in patients with advanced or metastatic solid tumours

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“We want to determine if Greenland sharks also show this traditional sign of aging or if their metabolism remains unaltered over time.” To measure the metabolism of the sharks, Mr Camplisson and his team conducted enzyme assays on preserved muscle tissue samples from Greenland sharks