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B12 Key Takeaways B12 is critical for DNA, red blood cells, and brain function† Deficiency is common, especially in older adults, vegetarians and vegans, and those with GI issues† A blood test is the only way to know if you’re deficient Supplements are effective and safe, especially when using the active form† Before starting any supplement, it’s important to talk with your physician or health care provider, especially if you suspect a B12 deficiency
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In these individuals it would appear that whilst they were able to exist as relatively healthy individuals, often not knowing that they had methylation associated mutations, some initiating factor such as a prolonged infection, combined with low vitamin D levels resulted in gradual loss of their vitamin B12 supplies leading to the CFS symptomatology being apparent, and the subsequent discovery of their methylation status