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Epigenetic reprograming in myalgic encephalomyelitis/chronic fatigue syndrome: A narrative of latent viruses - Apostolou - 2024 - Journal of Internal Medicine - Wiley Online Library

Preliminary clinical data and lab work suggest advantages for fertility, uterine recovery, and ovarian support, though large trials are still sparse

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For examples, βOHB-mediated inhibition of HDAC1 and HDAC2 increases acetylation of histone H3K9 and H3K14 and establishes a permissive chromatin configuration for the expression of Foxo3 with subsequent transcription of its downstream antioxidant genes such as catalase and MnSOD (172)