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By isolating the C-terminus of the human growth hormone molecule (tyrosine at the 176th position to phenylalanine at the 191st), researchers can study the potent fat-burning properties of HGH without the confounding variables of insulin-like growth factor (IGF-1) elevation or decreased insulin sensitivity

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The peptide is establishing its metabolic effects on fat tissue, but the total amount of fat oxidized over just 7-14 days is insufficient to produce measurable body composition changes