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doi: 10.3390/ijms22115495 120 CohenSJanicki-DevertsDDoyleWJMillerGEFrankERabinBSet al
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The clinical symptoms of functional constipation mainly include difficulty defecating, reduced frequency of defecation and dry stool ( Polysaccharides, as a class of natural macromolecular compounds with a variety of biological activities, are widely found in plants, animals and microorganisms ( Dendrobium officinale polysaccharide was proved to exert laxative effect through enhancing the gastrointestinal transit ratio, regulating gastrointestinal hormone levels and increasing fecal water content in constipated mice ( Gastrodia elata Blume polysaccharide significantly increased the abundance of probiotics (such as Bifidobacterium , Collinsella , Prevotella , and Faecalibacterium ) and inhibited the growth of pathogenics (such as Shigella , Dorea , Desulfovibrio , and Blautia ) to regulate the gut microbiota
