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The radioactive octreotide attaches to tumor cells that have receptors for somatostatin

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[1] [7] The longest CagriSema exposure reported to date is 84 weeks, in REDEFINE 4 — an open-label head-to-head against tirzepatide 15 mg in 809 participants, which did not meet its primary endpoint of non-inferiority on weight loss (23.0% versus 25.5%, or 20.2% versus 23.6% on the treatment-regimen estimand) and whose arm-level adverse-event rates have not been published

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