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However, the extent of this association is unclear since some studies have reported a 7.6-fold increase in the rate of colorectal cancers in acromegalic patients compared with control groups (275), whereas another study has reported as low as twofold increased risk of colorectal cancer in acromegalic patients (286, 287)

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Furthermore, it has been reported that both MARV and EBOV polymerases initiate RNA synthesis at +2 position on the EBOV 3’-leader 22