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quantified the hydrodynamic sizes of monomeric polyglutamine (which acts as a model IDP) as a function of chain length and showed that this homopolypeptide exists as a heterogeneous conformational ensemble of collapsed structures (Crick et al., 2006)
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Long-standing GERD with significant esophageal damage may require longer treatment periods and show slower response compared to milder, more recent-onset reflux
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