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Ces enzymes interviennent dans la glycolyse, la décarboxylation oxydative du pyruvate en acétyl-CoA, le cycle de l'acide tricarboxylique, la β-oxydation des acides gras et le métabolisme de l'alcool
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These differences are determined by genetic factors as well as nongenetic variables, such as commensal gut microbiota, age, sex, liver size, liver function, circadian rhythm, body temperature, and nutritional and environmental factors such as concomitant exposure to inducers or inhibitors of drug metabolism