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Outside the primary weight-loss interest, 5-Amino-1MQ is also discussed in research as a tool compound for studying NNMT’s broader role in metabolism, energy balance, and adipocyte (fat cell) biology

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In humans, hyperhomocysteine is related to cobalamin deficiency [52], whereas in dogs, homocysteine can be used mainly in the diagnosis of familiar cobalamin deficiency specifically in the Chinese Shar-Pei [53], but only after other diseases have been ruled out [54]