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Micronutrient Nutritional Test - Gina B. Healthy Registered Dietitian
(5) PRODH: Proline dehydrogenase (PRODH) is a mitochondrial flavoenzyme that catalyzes the first step of proline catabolism, converting proline into Δ 1 -pyrroline-5-carboxylate (P5C) while transferring electrons to ubiquinone (CoQ 10 ) in the mitochondrial ETC
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Preclinical studies have indicated that combining the MCT1 inhibitor AZD3965 with anti-PD-1 therapy lowers lactate release into the TME and boosts anti-tumor immunity (118)
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