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Research has demonstrated that the metabolite indole, which is associated with tryptophan metabolism, alleviates inflammatory responses by reducing the production of lipopolysaccharide-binding protein (LBP) and inhibiting the polarization of M1-type macrophages through activation of the intestinal 5-HT receptor HTR2B (Jiang L

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in 2020 showed no improvement in the CPR (OR = 1.15, 95% CI = 0.95 – 140) or LBR (0.94, 95% CI = 0.41- 2.15) when AOXs were given to women treated with IVF or ICSI (188)