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Another abnormality present in patients with ME/CFS is the presence of fibrinolysis-resistant amyloid fibrin microbleeds and platelet hyperactivation [78], which could also be a consequence of the overproduction of proinflammatory cytokines or due to the binding of EBERs to TLR3 [231–233, 308, 309]

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As a serious public health problem, hearing loss has resulted in growing disease burden, especially among the older population (183,184)