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(2016) reported that the presence of LKB1 promoted AMPK activity and its absence worked oppositely in high-fat diet-induced mice (HFD)

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One published study showed 5-Amino-1MQ has anti-proliferative activity in HeLa cells (PMID: 33645410), but the net effect of NNMT inhibition on cancer risk over long-term use is unknown

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