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Residual solvents from the synthesis process are invisible and odorless at the concentrations typically found in poorly manufactured peptides

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HSC activation is driven by both intracellular signals, such as the TGFβ/Smad, Notch, and Wnt/β-catenin pathways, and extracellular stimuli from other liver cells or external factors like cytokines and viral infections (Yan et al., 2021)