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Once high ROS levels have helped to stabilise HIF, it brings about this shift away from FAO by preventing transcription of PPARAα, a master upregulator of fat metabolism [120]
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When the HA-ss-FA concentration was 6 mg/mL, DOX was encapsulated into the hydrophobic core of the micelles with high efficiency (the EE and DL were 88.09 and 22.70%, respectively)
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