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Furthermore, sn2-15-hydroperoxy-eicasotetraenoyl-phosphatidylethanolamines (sn2-15-HpETE-PE) generated by 15-LOX phosphatidylethanolamine binding protein-1 (PEBP1) complex can serve as a marker for ferroptosis (Dobrian et al., 2011)

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Immunohistochemical analysis displayed that metformin did not reduce MMP13 expression and only partially decreased ADAMTS5 levels, and Collagen II in Nrf2 KO mice were not significantly influenced by metformin treatment (Fig

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