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It is notable that mTOR requires constant amino acid input 146 , while KRAS drives macropinocytosis 22 , and thus, pathway selection of glutamine catabolism by these two pathways may reflect differing metabolic requirements that we do not yet fully appreciate

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Ortler et al., 2008) was up-regulated on microglia throughout de- and remyelination (Olah et al., 2012)