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When PAMPs are recognized, the host is “warned” of the presence of infection, initially developing a direct antifungal response through phagocytic processes followed by pro-inflammatory and antimicrobial responses through the activation of different intracellular pathways via transcription factors, kinases or adaptor molecules, leading to gene expression, and the production of cytokines and chemokines, among others (Akira and Takeda, Thus, PRR recognition initiates effector and modulatory functions of phagocytic cells (Bachiega et al., 2015)

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The relationship of depression and stressors to immunological assays: a meta-analytic review